"Increased urea out of proportion to creatinine indicative of massive blood meal" Blood contains large number of proteins -> Upper GI bleeding -> blood enters GI tract -> Digestion of blood and its constituents -> Digestion of proteins -> increased production of urea (which is normally produced upon protein digestion) -> creatinine not affected because renal function is still normal -> Increased urea out of proportion to creatinine -> indicative of massive blood meal
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